Lenalidomide 5 mg is a thalidomide analogue. It is an immunomodulatory agent with the properties of antiangiogenic and antineoplastic.
It is an off-white to pale-yellow solid powder and soluble in organic solvents and low pH solutions.
It is an asymmetric carbon atom and might exist in S (-), R (+) optically active forms.
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Lenalidomide inhibits the growth of multiple myeloma cells and MM. IS cells (human multiple myeloma cell line) from
patients by inducing apoptosis and arrest of the cell cycle.
It inhibits the expression of cyclooxygenase-2 (COX-2) in vitro.
The tablet increases the inflammation of anti-inflammatory cytokines and inhibits the pro-inflammatory cytokines
secretion from peripheral blood mononuclear cells.
It enhances the immune system that indirectly fights cancer cells and obstructs the growth of new blood vessels in
cancer cells and chemical messengers.
Discuss with your doctor if you have a medical history of heart, liver, kidney, diseases, thyroid issues, or lactose
disorders, or if you are already on any medication for other diseases as Lenalidomide may cause irreversible effects
when taken in combination with other medicines.
A few people may live longer, and a few might die sooner than expected if they have the white blood cells and tumor
cells more in number. Therefore, talk to your doctor about all the risks, benefits, advantages, and disadvantages of the
medicine.
