Tenofovir Disoproxil Fumarate (300mg) + Efavirenz (600mg) + Emtricitabine (200mg) is an antiviral medicine and the fixed dosage combination and should be taken on the doctor’s prescription.
It is prescribed in combination with other HIV medicines.
Tenofovir DF:Tenofovir Disoproxil Fumarate is made from fumaric acid salt of bis isopropoxycarbonyloxymethyl ester derivative of Tenofovir.
It is white to off-white crystalline powder and has an Octanol/phosphate buffer pH 6.5 partition coefficient (log p) of 1.25 at 25 degrees centigrade.
It is a pro drug and a nucleoside reverse transcriptase inhibitor analog of adenosine. it is analog of adenosine 5- monophosphate that blocks RNA dependant DNA polymerase resulting in the inhibition of viral replication.
It inhibits the replication of HBV by blocking in HBV polymerase.
Efavirenz: It belongs to non-nucleoside reverse transcriptase inhibitors. It improves the nervous system’s tolerability to adverse reactions. It reduces the amount of virus in blood.
Emtricitabine: It is a nucleoside reverse-transcriptase inhibitor. It is a synthetic nucleoside analog of cytidine and phosphorylated by cellular enzymes to form Emtricitabine 5-Triphosphate.
The trio combination is used to treat HIV infection in the body. It restricts the spread of infection and strengthens the immune system to fight the viruses and infections by reducing the amount of HIV in the blood.
It lowers the risk of other infections, viruses entering in to the body.
Using protection during sex, not sharing personal items like toothbrush, razors, needles/syringes with uninfected persons and taking necessary precautions along with the
medicine would help in effective treatment.
Take the medicine by mouth on empty stomach
See your doctor and discuss all the cons and pros of the medicine and seek medical help immediately in case of adverse reactions.
The medicine is inhibited in pregnant ladies, planning for pregnancy, or breast feeding mothers. They have to contact their doctors if taking the medicine is unavoidable.
Observe the after effects of the medicine and seek medical help immediately if the conditions worsen.